Is widespread antibiotic use really necessary? Secondary Bacterial Infections in COVID-19 Patients: Maataoui N, et al. Impact of rapid multiplex PCR on management of antibiotic therapy in COVID-19-positive patients hospitalized in intensive care unit o-infections in COVID-19 critically ill and antibiotic management: a prospective cohort analysis.Co-infections in COVID-19 critically ill and antibiotic management: a prospective cohort analysis. Evaluation of the BioFire FilmArray Pneumonia Panel for Detection of Viral and Bacterial Pathogens in Lower Respiratory Tract Specimens in the Setting of a Tertiary Care Academic Medical Center. Multicenter evaluation of a syndromic rapid multiplex PCR test for early adaptation of antimicrobial therapy in adult patients with pneumonia. Practical Comparison of the BioFire FilmArray Pneumonia Panel to Routine Diagnostic Methods and Potential Impact on Antimicrobial Stewardship in Adult Hospitalized Patients with Lower Respiratory Tract Infections. Antimicrobial Resistance Management Solutions page.Emergency Department patient management Solutions page.“Pneumonia as the Most Common Lower Respiratory Tract Infection”. “Prevalence of Inappropriate Antibiotic Prescriptions Among US Ambulatory Care Visits, 2010-2011”. 3,4 This contributes to longer hospital stays and higher costs, as well as to the development of antimicrobial resistance. Inappropriate antibiotic treatment for pneumonia is common, in part because it is often treated empirically without determining the cause. 2, Aside from the symptoms, x-rays, demographic information and identification of potential causative agents are important for making a diagnosis of pneumonia. Pneumonia can be difficult to diagnose because the typical symptoms – shortness of breath, weakness, high fever, coughing, and fatigue – can also signal other illnesses, and the symptoms may not be pathogen specific. The BIOFIRE ® FILMARRAY ® Pneumonia plus Panel is incredibly comprehensive, with simultaneous testing for 27 of the most common pathogens involved in LRTI and 7 genetic markers of antibiotic resistance. BIOFIRE ® FILMARRAY ® Respiratory Panels (RP) panels.BIOFIRE ® FILMARRAY ® Gastrointestinal (GI) panel.BIOFIRE ® FILMARRAY ® Blood Culture Identification Panel (BCID) panel.BIOFIRE ® FILMARRAY ® Meningitis Encephalitis (ME) panel.Taken together, the five BIOFIRE ® FILMARRAY ® Panels comprise the largest infectious disease pathogen menu commercially available. The BIOFIRE ® FILMARRAY ® Pneumonia plus Panel and the BIOFIRE ® FILMARRAY ® Pneumonia Panel are one of five FDA-cleared and CE-marked panels for use on the BIOFIRE ® FILMARRAY ® multiplex PCR system. Comprehensive: 34-target pneumonia panel.Easy: No precise measuring or pipetting required.A rapid diagnosis can assist with directing appropriate infection control practices thereby aiding in the prevention of secondary spread of infection, shorten hospital stays, reduce ancillary testing, and reduceoverall health care costs. For, A rapid and accurate identification of the causative agent of both community and health care associated respiratory infections can help improve patient management by informing timely and effective antibiotic or antiviral therapy. The new panel complements the existing BIOFIRE ® FILMARRAY ® Respiratory 2 plus Panel to provide a comprehensive diagnostic tool for pneumonia and other lower respiratory tract infections. The system integrates sample preparation, nucleic acid extraction and purification, amplification, detection and analysis into one simple system that requires just 2 minutes of hands-on time, with a total run time of about one hour. The BIOFIRE ® FILMARRAY ® Pneumonia plus Panel is run on the BIOFIRE ® FILMARRAY ® System, a US FDA, CE-IVD, and TGA certified multiplex PCR system. It offers an overall sensitivity and specificity for bronchoalveolar (BAL)-like samples of 96,2% and 98.3%, respectively, and for sputum samples a sensitivity and specificity of 96.3% and 97.2%, respectively. The BIOFIRE ® FILMARRAY ® Pneumonia plus Panel tests for 18 bacteria (11 Gram negative, 4 Gram positive and 3 atypical), 7 antibiotic resistance markers, and 9 viruses that cause pneumonia and other lower respiratory tract infections. Simple, comprehensive pneumonia and LRTI testing

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